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Monday, March 5, 2012

Vaginal diazepam use with urogenital pain/ pelvic floor dysfunction

Vaginal diazepam use with urogenital pain/ pelvic floor dysfunction: serum diazepam levels and efficacy data.  Carrico DJ, Peters KM. Urological Nursing 2011;31(5):279-299.
This paper discusses the authors’ experience in using vaginal valium for pelvic floor muscle dysfunction and pain in 21 women.  This is not a randomized control trial. Dosing was 2 to 10 mg up to every 8 hours.  Usual start 5 mg increasing to 10 mg after 7 to 10 days if needed.  Oral tablet was crushed and mixed with vaginal lubricant or the tablet was inserted whole into the vagina.  15 women used vaginal valium 2 to 3 times per day; the remaining used it 1 to 7 times per week.  After one month 62% were moderately or markedly improved. 

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