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Tuesday, December 16, 2014

Myofascial Trigger Points of the Pelvic Floor: Associations with Urological Pain Syndromes and Treatment Strategies Including Injection therapy

Moldwin and Fariello
Curr Urol Rep (2013) 14:409-417

Journal Club 12/10/14 Jane OBrien Franczak, PT, MSPT

MTrP: Knots in taut muscle bands that produce pain, local or referred. Twitch response when palpated; active or Latent,

Trigger points of the pelvic floor are almost always accompanied by high tone  pelvic floor muscular dysfunction (HTPDF)

Pain with MTrP attributed to high local concentrations of inflammatory mediators, neuropeptides and neurotransmitters.

Stimulation of local nocioceptors elicits pain- local and referred.

Shah study: n=12, 3 groups- no pain, no TrP (normal)
                                                no pain, TrP present (latent)
                                                pain, TrP present (active)

Needle inserted to UT, advanced to elicit Local Twitch response (LTR) in active and latent groups. LTR confirmed  by EMG. Active group showed higher bradykinin, CGRP, substance P, TNF-Alpha, IL-Beta, serotonin and norepinephrine than nl group. pH lower in active group.

2008 repeat study on gastrocs. Same results  and increased IL-6 and IL-8 AND opposite uninvolved gastroc had same result of elevated chemicals in active group versus latent and normal groups.   Inflammatory response goes beyond focal process. (Central Sensitization? Fibro?)

MTrP also local nocioceptor sensitization, local ischemia and sustained release of acetylcholine. Results in local twitch response , contracture of sarcomeres and knots.

IC/BPS, CP/CPPS, Vulvodynia and MTrP

IC/BPS : cstics: urgency, frequency, PP, discomfort. May not be bladder based, but HTPFD and MTrP. Same for CP/CPPS and vulvodynia.
 
Many failed treatments or suboptimal results with organ based therapies.
 85% of IC/BPS have MTrP and HTPFD can account for irritative and obstructive void symptoms.
AUA guidelines for IC/BPS recommend PT for HTPFD.
Berger study found that men with CP/CPPS have both int. and ext. MTrP assoc with increase pain in non-prostatic locations.
Involves entire pelvis.
Label of Prostatitis  can misguide the plan.
Women with vulvodynia- Pain cycle of HTPFS lead to decreased strength and TrP from clenching. (Defense reaction).

HTPFD has been postulated to activate vulvar mucosal sensitivities. Leads to viscous cycle. IC may resolve when bladder treatment fail and therapy is directed to MTrP. So, good history taking and exam needed to properly ID MTrP.

Treatment of MTrP

Must treat underlying cause and active TrP.
Treat via Behavior Modification : modalities, biofeedback, avoid Kegel and Valsalva, paradoxical relaxation.
 Control Constipation: Often found with chronic PP due to Hypertonic PF
Heat, Ms. Relaxants,
Physical Therapy: stretching, MFR. Studies show Myofascial treatment had best results.
Trigger Point injections
Dry Needling:

Literature indicated that needle effect is more important than substance injected. Ay et al study showed substance injected isnt as important as injection itself.

Tsai study showed beneficial effects distant to site of injection. Pts with unilateral shoulder pain from MTrP at UT received sham needling to ECR , control: Dry needling to ECR.   Statistically improved pain, Cervical spine ROM as compared to control group. ( No mention of results at shoulder)
Good for CPP pts too sensitive to receive needle to primary area of pain.

How does it work?

1.  Mechanical disruption of ms. Fibers and nerve endings depolarize nerve endings
2.  Interruption of pos. feedback loop that perpetuates pain
3.  Dilution of nociceptive substances by anesthetic
4.  Vasodilation from anesthetic to remove excess metabolites
5.  Endorphin release
6.  Release of nocioceptive /inflammatory biochemical
Injections versus dry needling can be beneficial to decrease post injection soreness.
Injection Technique
25 or 27 gauge needle  1.5 in 8 in. Guided to vaginal, sub gluteal and perineal region. Stretching of Theiles massage afterwards. Up to 3 treatments for relief.

Discussion
1.  Clinical Applications:
2.  Experiences with Dry Needling or pts who have had injections

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