Nijs
J, Van Houdenhove B, Oostendrop RAB. Manual Therapy 2010 15:135-141.
Pelvic
PT distance journal club 3/5/14
Beth
Shelly PT, DPT, WCS, BCB PMD
Mechanism
based clinical guidelines using medical diagnosis and history, clinical
examination
·
Primary
hyperalgesia - acute pain - several days - sensitization of the nociceptors to
protect from further damage - local phenomenon
·
Secondary
hyperalgesia - chronic pain - increased
responsiveness of dorsal horn neurons in the spinal segments of the primary
nociceptors - central sensitization
Central
sensitization (CS) - defined by Meyer 1995 - "an augmentation of
responsiveness of central neurons to input from unimodal and polymodal
receptors."
·
Altered
sensory processing in the brain
·
Impaired
descending inhibition of pain
·
Overactive
ascending pain facilitatory pathways
·
Temporal
summation of secondary pain = wind up
·
Long
term enhancement of synapses in some areas of the brain
·
Net
result
o Augmented
nociceptive signal
o Increase
responsiveness to a variety of peripheral stimuli
o Decrease
tolerance of senses